Mitochondrially targeted tamoxifen alleviates markers of obesity and type 2 diabetes mellitus in mice

Type 2 diabetes mellitus represents a major health problem with increasing prevalence worldwide. Limited efficacy of current therapies has prompted a search for novel therapeutic options. Here we show that treatment of pre-diabetic mice with mitochondrially targeted tamoxifen, a potential anti-cance...

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Detalles Bibliográficos
Autores principales: Vacurova, Eliska, Trnovska, Jaroslava, Svoboda, Petr, Skop, Vojtech, Novosadova, Vendula, Reguera, David Pajuelo, Petrezselyová, Silvia, Piavaux, Benoit, Endaya, Berwini, Spoutil, Frantisek, Zudova, Dagmar, Stursa, Jan, Melcova, Magdalena, Bielcikova, Zuzana, Werner, Lukas, Prochazka, Jan, Sedlacek, Radislav, Huttl, Martina, Hubackova, Sona Stemberkova, Haluzik, Martin, Neuzil, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987092/
https://www.ncbi.nlm.nih.gov/pubmed/35387987
http://dx.doi.org/10.1038/s41467-022-29486-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987092/
https://www.ncbi.nlm.nih.gov/pubmed/35387987
http://dx.doi.org/10.1038/s41467-022-29486-z

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