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Alloimmunity to Class 2 Human Leucocyte Antigens May Reduce HIV-1 Acquisition – A Nested Case-Control Study in HIV-1 Serodiscordant Couples

Enveloped viruses, including the Human Immunodeficiency Virus-1 (HIV), incorporate host proteins such as human leucocyte antigens (HLA) into their envelope. Pre-existing antibodies against HLA, termed HLA antibodies, may bind to these surface proteins and reduce viral infectivity. Related evidence i...

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Detalles Bibliográficos
Autores principales: Suchard, Melinda S., Martinson, Neil, Malfeld, Susan, de Assis Rosa, Debbie, Mackelprang, Romel D., Lingappa, Jairam, Hou, Xuanlin, Rees, Helen, Delany-Moretlwe, Sinead, Goldfein, Hadassa, Ranchod, Heena, Coetzee, David, Otwombe, Kennedy, Morris, Lynn, Tiemessen, Caroline T., Savulescu, Dana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987441/
https://www.ncbi.nlm.nih.gov/pubmed/35401581
http://dx.doi.org/10.3389/fimmu.2022.813412