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Is It Possible to Separate the Graft-Versus-Leukemia (GVL) Effect Against B Cell Acute Lymphoblastic Leukemia From Graft-Versus-Host Disease (GVHD) After Hematopoietic Cell Transplant?

Hematopoietic cell transplant is a curative therapy for many pediatric patients with high risk acute lymphoblastic leukemia. Its therapeutic mechanism is primarily based on the generation of an alloreactive graft-versus-leukemia effect that can eliminate residual leukemia cells thus preventing relap...

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Detalles Bibliográficos
Autores principales: Rozmus, Jacob, Bhatt, Sima T., Buxbaum, Nataliya Prokopenko, Cuvelier, Geoffrey D. E., Li, Amanda M., Kitko, Carrie L., Schultz, Kirk R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987503/
https://www.ncbi.nlm.nih.gov/pubmed/35402356
http://dx.doi.org/10.3389/fped.2022.796994