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Is It Possible to Separate the Graft-Versus-Leukemia (GVL) Effect Against B Cell Acute Lymphoblastic Leukemia From Graft-Versus-Host Disease (GVHD) After Hematopoietic Cell Transplant?
Hematopoietic cell transplant is a curative therapy for many pediatric patients with high risk acute lymphoblastic leukemia. Its therapeutic mechanism is primarily based on the generation of an alloreactive graft-versus-leukemia effect that can eliminate residual leukemia cells thus preventing relap...
Autores principales: | Rozmus, Jacob, Bhatt, Sima T., Buxbaum, Nataliya Prokopenko, Cuvelier, Geoffrey D. E., Li, Amanda M., Kitko, Carrie L., Schultz, Kirk R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987503/ https://www.ncbi.nlm.nih.gov/pubmed/35402356 http://dx.doi.org/10.3389/fped.2022.796994 |
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