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Integration of Adverse Outcome Pathways, Causal Networks and ‘Omics to Support Chemical Hazard Assessment

Several approaches have been used in an attempt to simplify and codify the events that lead to adverse effects of chemicals including systems biology, ‘omics, in vitro assays and frameworks such as the Adverse Outcome Pathway (AOP). However, these approaches are generally not integrated despite thei...

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Detalles Bibliográficos
Autores principales: Perkins, Edward J., Woolard, E. Alice, Garcia-Reyero, Natàlia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987526/
https://www.ncbi.nlm.nih.gov/pubmed/35399296
http://dx.doi.org/10.3389/ftox.2022.786057