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Integration of Adverse Outcome Pathways, Causal Networks and ‘Omics to Support Chemical Hazard Assessment
Several approaches have been used in an attempt to simplify and codify the events that lead to adverse effects of chemicals including systems biology, ‘omics, in vitro assays and frameworks such as the Adverse Outcome Pathway (AOP). However, these approaches are generally not integrated despite thei...
Autores principales: | Perkins, Edward J., Woolard, E. Alice, Garcia-Reyero, Natàlia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987526/ https://www.ncbi.nlm.nih.gov/pubmed/35399296 http://dx.doi.org/10.3389/ftox.2022.786057 |
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