Neuroinflammation Upregulated Neuronal Toll-Like Receptors 2 and 4 to Drive Synucleinopathy in Neurodegeneration

Background: Parkinson’s disease (PD) is characterized by intraneuronal α-synuclein aggregation called Lewy bodies and progressive dopaminergic neurodegeneration. Toll-like receptor (TLR) signaling is a major pathway mediating inflammation. The molecular link on how neuroinflammation upregulates neur...

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Detalles Bibliográficos
Autores principales: Chung, Lucia Yi-Ru, Lin, Yi-Ting, Liu, Chi, Tai, Yi-Cheng, Lin, Han-Yi, Lin, Chin-Hsien, Chen, Ching-Chow
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987529/
https://www.ncbi.nlm.nih.gov/pubmed/35401198
http://dx.doi.org/10.3389/fphar.2022.845930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987529/
https://www.ncbi.nlm.nih.gov/pubmed/35401198
http://dx.doi.org/10.3389/fphar.2022.845930

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