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Neuroinflammation Upregulated Neuronal Toll-Like Receptors 2 and 4 to Drive Synucleinopathy in Neurodegeneration
Background: Parkinson’s disease (PD) is characterized by intraneuronal α-synuclein aggregation called Lewy bodies and progressive dopaminergic neurodegeneration. Toll-like receptor (TLR) signaling is a major pathway mediating inflammation. The molecular link on how neuroinflammation upregulates neur...
Autores principales: | Chung, Lucia Yi-Ru, Lin, Yi-Ting, Liu, Chi, Tai, Yi-Cheng, Lin, Han-Yi, Lin, Chin-Hsien, Chen, Ching-Chow |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987529/ https://www.ncbi.nlm.nih.gov/pubmed/35401198 http://dx.doi.org/10.3389/fphar.2022.845930 |
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