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Public T-Cell Receptors (TCRs) Revisited by Analysis of the Magnitude of Identical and Highly-Similar TCRs in Virus-Specific T-Cell Repertoires of Healthy Individuals

Since multiple different T-cell receptor (TCR) sequences can bind to the same peptide-MHC combination and the number of TCR-sequences that can theoretically be generated even exceeds the number of T cells in a human body, the likelihood that many public identical (PUB-I) TCR-sequences frequently con...

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Detalles Bibliográficos
Autores principales: Huisman, Wesley, Hageman, Lois, Leboux, Didier A. T., Khmelevskaya, Alexandra, Efimov, Grigory A., Roex, Marthe C. J., Amsen, Derk, Falkenburg, J. H. Frederik, Jedema, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987591/
https://www.ncbi.nlm.nih.gov/pubmed/35401538
http://dx.doi.org/10.3389/fimmu.2022.851868