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Public T-Cell Receptors (TCRs) Revisited by Analysis of the Magnitude of Identical and Highly-Similar TCRs in Virus-Specific T-Cell Repertoires of Healthy Individuals
Since multiple different T-cell receptor (TCR) sequences can bind to the same peptide-MHC combination and the number of TCR-sequences that can theoretically be generated even exceeds the number of T cells in a human body, the likelihood that many public identical (PUB-I) TCR-sequences frequently con...
Autores principales: | Huisman, Wesley, Hageman, Lois, Leboux, Didier A. T., Khmelevskaya, Alexandra, Efimov, Grigory A., Roex, Marthe C. J., Amsen, Derk, Falkenburg, J. H. Frederik, Jedema, Inge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987591/ https://www.ncbi.nlm.nih.gov/pubmed/35401538 http://dx.doi.org/10.3389/fimmu.2022.851868 |
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