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Afatinib Mediates Autophagic Degradation of ORAI1, STIM1, and SERCA2, Which Inhibits Proliferation of Non–Small Cell Lung Cancer Cells

BACKGROUND: The expression of calcium signaling pathway molecules is altered in various carcinomas, which are related to the proliferation and altered characteristics of cancer cells. However, changes in calcium signaling in anti-cancer drug-resistant cells (bearing a T790M mutation in epidermal gro...

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Detalles Bibliográficos
Autores principales: Kim, Mi Seong, Kim, So Hui, Yang, Sei-Hoon, Kim, Min Seuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Tuberculosis and Respiratory Diseases 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987670/
https://www.ncbi.nlm.nih.gov/pubmed/34847639
http://dx.doi.org/10.4046/trd.2021.0095