TNFR2 blockade of regulatory T cells unleashes an antitumor immune response after hematopoietic stem-cell transplantation

BACKGROUND: Targeting immune checkpoints that inhibit antitumor immune responses has emerged as a powerful new approach to treat cancer. We recently showed that blocking the tumor necrosis factor receptor-type 2 (TNFR2) pathway induces the complete loss of the protective function of regulatory T cel...

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Detalles Bibliográficos
Autores principales: Moatti, Audrey, Debesset, Anais, Pilon, Caroline, Beldi-Ferchiou, Asma, Leclerc, Mathieu, Redjoul, Rabah, Charlotte, Frederic, To, Nhu Hanh, Bak, Adeline, Belkacemi, Yazid, Salomon, Benoît Laurent, Issa, Fadi, Michonneau, David, Maury, Sebastien, Cohen, José Laurent, Thiolat, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987798/
https://www.ncbi.nlm.nih.gov/pubmed/35387779
http://dx.doi.org/10.1136/jitc-2021-003508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987798/
https://www.ncbi.nlm.nih.gov/pubmed/35387779
http://dx.doi.org/10.1136/jitc-2021-003508

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