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Circulating exosomal miR-21 mediates HUVEC proliferation and migration through PTEN/PI3K/AKT in Crohn’s disease

BACKGROUND: Angiogenesis and vascular dysfunction play important roles in the occurrence and development of Crohn’s disease (CD), but relevant mechanistic research is lacking. This paper aimed to use exosomal technology to elucidate the mechanism of vascular abnormalities in CD. METHODS: Ultra-high-...

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Detalles Bibliográficos
Autores principales: Xie, Xiaoran, Qu, Peng, Wu, Hao, Liu, Peng, Luo, Ju, Chi, Jingshu, Liu, Xiaoming, Chen, Xiong, Xu, Canxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987870/
https://www.ncbi.nlm.nih.gov/pubmed/35402577
http://dx.doi.org/10.21037/atm-22-475