TRPC6 ameliorates renal ischemic reperfusion injury by inducing Zn(2+) influx and activating autophagy to resist necrosis

BACKGROUND: Renal ischemic reperfusion injury (RIRI) is the most hackneyed cause of acute renal injury with high incidence. As a slit diaphragm (SD), TRPC6 (transient receptor potential channel 6) can maintain the structure and function of glomerular podocytes, and its activation has been reported t...

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Detalles Bibliográficos
Autores principales: Pu, Youmin, Zhao, Hongwen, Shen, Bingbing, Zhou, Qiang, Xie, Pan, Wu, Xiongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987871/
https://www.ncbi.nlm.nih.gov/pubmed/35402594
http://dx.doi.org/10.21037/atm-21-5837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987871/
https://www.ncbi.nlm.nih.gov/pubmed/35402594
http://dx.doi.org/10.21037/atm-21-5837

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