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Assessment of Patient-Specific Human Leukocyte Antigen Genomic Loss at Relapse After Antithymocyte Globulin–Based T-Cell–Replete Haploidentical Hematopoietic Stem Cell Transplant

IMPORTANCE: Patient-specific human leukocyte antigen (HLA) genomic loss (HLA loss) is one of the reputed mechanisms of leukemia immune escape and relapse after haploidentical hematopoietic stem cell transplant (HSCT). However, clinical characteristics and prognosis of this distinct relapse type in t...

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Detalles Bibliográficos
Autores principales: Wu, Hengwei, Shi, Jimin, Luo, Yi, Yu, Jian, Lai, Xiaoyu, Liu, Lizhen, Fu, Huarui, Ouyang, Guifang, Xu, Xiaojun, Xiao, Haowen, Huang, He, Zhao, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987901/
https://www.ncbi.nlm.nih.gov/pubmed/35385089
http://dx.doi.org/10.1001/jamanetworkopen.2022.6114