Cerebellar Pathology in an Inducible Mouse Model of Friedreich Ataxia

Friedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused by deficiency of the mitochondrial protein frataxin. Lack of frataxin causes neuronal loss in various areas of the CNS and PNS. In particular, cerebellar neuropathology in FRDA patients includes loss of large princi...

Descripción completa

Detalles Bibliográficos
Autores principales: Mercado-Ayón, Elizabeth, Warren, Nathan, Halawani, Sarah, Rodden, Layne N., Ngaba, Lucie, Dong, Yi Na, Chang, Joshua C., Fonck, Carlos, Mavilio, Fulvio, Lynch, David R., Lin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987918/
https://www.ncbi.nlm.nih.gov/pubmed/35401081
http://dx.doi.org/10.3389/fnins.2022.819569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987918/
https://www.ncbi.nlm.nih.gov/pubmed/35401081
http://dx.doi.org/10.3389/fnins.2022.819569

Ejemplares similares