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Cerebellar Pathology in an Inducible Mouse Model of Friedreich Ataxia

Friedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused by deficiency of the mitochondrial protein frataxin. Lack of frataxin causes neuronal loss in various areas of the CNS and PNS. In particular, cerebellar neuropathology in FRDA patients includes loss of large princi...

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Detalles Bibliográficos
Autores principales:	Mercado-Ayón, Elizabeth, Warren, Nathan, Halawani, Sarah, Rodden, Layne N., Ngaba, Lucie, Dong, Yi Na, Chang, Joshua C., Fonck, Carlos, Mavilio, Fulvio, Lynch, David R., Lin, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987918/ https://www.ncbi.nlm.nih.gov/pubmed/35401081 http://dx.doi.org/10.3389/fnins.2022.819569

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