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Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis

Diabetic nephropathy (DN) is quickly becoming the largest cause of end-stage renal disease (ESRD) in diabetic patients, as well as a major source of morbidity and mortality. Our previous studies indicated that the activation of Nrf2/ARE pathway via Connexin43 (Cx43) considerably contribute to the pr...

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Detalles Bibliográficos
Autores principales: Chen, Rui, Zeng, Jingran, Li, Chuting, Xiao, Haiming, Li, Shanshan, Lin, Zeyuan, Huang, Kaipeng, Shen, Juan, Huang, Heqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987976/
https://www.ncbi.nlm.nih.gov/pubmed/35401165
http://dx.doi.org/10.3389/fphar.2022.853383