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Development of oxaalkyne and alkyne fatty acids as novel tracers to study fatty acid beta-oxidation pathways and intermediates

Fatty acid beta-oxidation is a key process in mammalian lipid catabolism. Disturbance of this process results in severe clinical symptoms, including dysfunction of the liver, a major beta-oxidizing tissue. For a thorough understanding of this process, a comprehensive analysis of involved fatty acid...

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Detalles Bibliográficos
Autores principales: Kuerschner, Lars, Leyendecker, Philipp, Klizaite, Kristina, Fiedler, Maria, Saam, Jennifer, Thiele, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988009/
https://www.ncbi.nlm.nih.gov/pubmed/35247455
http://dx.doi.org/10.1016/j.jlr.2022.100188