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O-GlcNAc transferase promotes the nuclear localization of the focal adhesion–associated protein Zyxin to regulate UV-induced cell death

Zyxin is a zinc-binding phosphoprotein known to regulate cell migration, adhesion, and cell survival. Zyxin also plays a role in signal transduction between focal adhesions and the nuclear compartment. However, the mechanism of Zyxin shuttling to nucleus is still unclear. Here, we identify that the...

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Detalles Bibliográficos
Autores principales: Zhao, Yuhang, Yue, Shichao, Zhou, Xin, Guo, Jing, Ma, Shuyun, Chen, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988012/
https://www.ncbi.nlm.nih.gov/pubmed/35227760
http://dx.doi.org/10.1016/j.jbc.2022.101776