Human Nmnat1 Promotes Autophagic Clearance of Amyloid Plaques in a Drosophila Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by irreversible cognitive decline with limited therapeutic approaches. We characterized a Drosophila model of amyloid pathology that expresses human amyloid-beta precursor protein (APP(695)) and β-site APP cleaving enz...

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Detalles Bibliográficos
Autores principales: Zhu, Yi, Lobato, Amanda G., Zhai, R. Grace, Pinto, Milena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988035/
https://www.ncbi.nlm.nih.gov/pubmed/35401143
http://dx.doi.org/10.3389/fnagi.2022.852972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988035/
https://www.ncbi.nlm.nih.gov/pubmed/35401143
http://dx.doi.org/10.3389/fnagi.2022.852972

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