Three-Day Continuous Oxytocin Infusion Attenuates Thermal and Mechanical Nociception by Rescuing Neuronal Chloride Homeostasis via Upregulation KCC2 Expression and Function

Oxytocin (OT) and its receptor are promising targets for the treatment and prevention of the neuropathic pain. In the present study, we compared the effects of a single and continuous intrathecal infusion of OT on nerve injury-induced neuropathic pain behaviours in mice and further explore the mecha...

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Detalles Bibliográficos
Autores principales: Ba, Xiyuan, Ran, Chenqiu, Guo, Wenjun, Guo, Jing, Zeng, Qian, Liu, Tao, Sun, Wuping, Xiao, Lizu, Xiong, Donglin, Huang, Yelan, Jiang, Changyu, Hao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988046/
https://www.ncbi.nlm.nih.gov/pubmed/35401174
http://dx.doi.org/10.3389/fphar.2022.845018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988046/
https://www.ncbi.nlm.nih.gov/pubmed/35401174
http://dx.doi.org/10.3389/fphar.2022.845018

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