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COX4-1 promotes mitochondrial supercomplex assembly and limits reactive oxide species production in radioresistant GBM

Glioblastoma (GBM) is a fatal disease with recurrences often associated with radioresistance. Although often effective at treating newly diagnosed GBM, increasing evidence suggests that radiotherapy-induced alterations in tumor metabolism promote GBM recurrence and aggressiveness. Using isogenic rad...

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Detalles Bibliográficos
Autores principales: Oliva, Claudia R., Ali, Md Yousuf, Flor, Susanne, Griguer, Corinne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988053/
https://www.ncbi.nlm.nih.gov/pubmed/35478774
http://dx.doi.org/10.15698/cst2022.04.266