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Retinoic Acid Induces an IFN-Driven Inflammatory Tumour Microenvironment, Sensitizing to Immune Checkpoint Therapy

With immune checkpoint therapy (ICT) having reshaped the treatment of many cancers, the next frontier is to identify and develop novel combination therapies to improve efficacy. Previously, we and others identified beneficial immunological effects of the vitamin A derivative tretinoin on anti-tumour...

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Detalles Bibliográficos
Autores principales: Tilsed, Caitlin M., Casey, Thomas H., de Jong, Emma, Bosco, Anthony, Zemek, Rachael M., Salmons, Joanne, Wan, Graeme, Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lesterhuis, Willem Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988133/
https://www.ncbi.nlm.nih.gov/pubmed/35402250
http://dx.doi.org/10.3389/fonc.2022.849793