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Retinoic Acid Induces an IFN-Driven Inflammatory Tumour Microenvironment, Sensitizing to Immune Checkpoint Therapy
With immune checkpoint therapy (ICT) having reshaped the treatment of many cancers, the next frontier is to identify and develop novel combination therapies to improve efficacy. Previously, we and others identified beneficial immunological effects of the vitamin A derivative tretinoin on anti-tumour...
Autores principales: | Tilsed, Caitlin M., Casey, Thomas H., de Jong, Emma, Bosco, Anthony, Zemek, Rachael M., Salmons, Joanne, Wan, Graeme, Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lesterhuis, Willem Joost |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988133/ https://www.ncbi.nlm.nih.gov/pubmed/35402250 http://dx.doi.org/10.3389/fonc.2022.849793 |
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