Autologous, lentivirus‐modified, T‐rapa cell “micropharmacies” for lysosomal storage disorders

T cells are the current choice for many cell therapy applications. They are relatively easy to access, expand in culture, and genetically modify. Rapamycin‐conditioning ex vivo reprograms T cells, increasing their memory properties and capacity for survival, while reducing inflammatory potential and...

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Detalles Bibliográficos
Autores principales: Nagree, Murtaza S, Felizardo, Tania C, Faber, Mary L, Rybova, Jitka, Rupar, C Anthony, Foley, S Ronan, Fuller, Maria, Fowler, Daniel H, Medin, Jeffrey A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988206/
https://www.ncbi.nlm.nih.gov/pubmed/35298086
http://dx.doi.org/10.15252/emmm.202114297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988206/
https://www.ncbi.nlm.nih.gov/pubmed/35298086
http://dx.doi.org/10.15252/emmm.202114297

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