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Autologous, lentivirus‐modified, T‐rapa cell “micropharmacies” for lysosomal storage disorders
T cells are the current choice for many cell therapy applications. They are relatively easy to access, expand in culture, and genetically modify. Rapamycin‐conditioning ex vivo reprograms T cells, increasing their memory properties and capacity for survival, while reducing inflammatory potential and...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988206/ https://www.ncbi.nlm.nih.gov/pubmed/35298086 http://dx.doi.org/10.15252/emmm.202114297 |