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Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice

BACKGROUND: Neuroinflammation is a crucial factor in the development of secondary brain injury after intracerebral hemorrhage (ICH). Irisin is a newly identified myokine that confers strong neuroprotective effects in experimental ischemic stroke. However, whether this myokine can exert neuroprotecti...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Tian, Mi, Tan, Jiaying, Pei, Xu, Lu, Chaocheng, Xin, Yuewen, Deng, Shuixiang, Zhao, Feng, Gao, Yanqin, Gong, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988353/
https://www.ncbi.nlm.nih.gov/pubmed/35392928
http://dx.doi.org/10.1186/s12974-022-02438-6