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Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer

BACKGROUND: Stanniocalcin 1 (STC1) plays an integral role in ovarian cancer (OC). However, the functional role of STC1 in metastasis, lipid metabolism and cisplatin (DDP) chemoresistance in OC is not fully understood. METHODS: Single-cell sequencing and IHC analysis were performed to reveal STC1 exp...

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Detalles Bibliográficos
Autores principales: Lin, Feikai, Li, Xiaoduan, Wang, Xinjing, Sun, Huizhen, Wang, Ziliang, Wang, Xipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988421/
https://www.ncbi.nlm.nih.gov/pubmed/35392966
http://dx.doi.org/10.1186/s13046-022-02315-3