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Enhanced Cancer Therapy Using an Engineered Designer Cytokine Alone and in Combination With an Immune Checkpoint Inhibitor

melanoma differentiation associated gene-7 or Interleukin-24 (mda-7, IL-24) displays expansive anti-tumor activity without harming corresponding normal cells/tissues. This anticancer activity has been documented in vitro and in vivo in multiple preclinical animal models, as well as in patients with...

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Detalles Bibliográficos
Autores principales: Pradhan, Anjan K., Bhoopathi, Praveen, Maji, Santanu, Kumar, Amit, Guo, Chunqing, Mannangatti, Padmanabhan, Li, Jiong, Wang, Xiang-Yang, Sarkar, Devanand, Emdad, Luni, Das, Swadesh K., Fisher, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988683/
https://www.ncbi.nlm.nih.gov/pubmed/35402258
http://dx.doi.org/10.3389/fonc.2022.812560