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The antimicrobial peptide S100A8/A9 produced by airway epithelium functions as a potent and direct regulator of macrophage phenotype and function

BACKGROUND: Elevated counts of alveolar macrophages and attenuated phagocytic capacity are associated with chronic obstructive pulmonary disease (COPD). Factors governing macrophage phagocytosis are poorly understood. In this study we aimed to compare the influence of airway epithelial cell secretio...

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Detalles Bibliográficos
Autores principales: Skronska-Wasek, Wioletta, Durlanik, Sibel, Le, Huy Quang, Schroeder, Victoria, Kitt, Kerstin, Garnett, James Peter, Pflanz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989056/
https://www.ncbi.nlm.nih.gov/pubmed/34561292
http://dx.doi.org/10.1183/13993003.02732-2020