Impairment of SARS-CoV-2 spike glycoprotein maturation and fusion activity by nitazoxanide: an effect independent of spike variants emergence

SARS-CoV-2, the causative agent of COVID-19, has caused an unprecedented global health crisis. The SARS-CoV-2 spike, a surface-anchored trimeric class-I fusion glycoprotein essential for viral entry, represents a key target for developing vaccines and therapeutics capable of blocking virus invasion....

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Detalles Bibliográficos
Autores principales: Riccio, Anna, Santopolo, Silvia, Rossi, Antonio, Piacentini, Sara, Rossignol, Jean-Francois, Santoro, M. Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989121/
https://www.ncbi.nlm.nih.gov/pubmed/35391601
http://dx.doi.org/10.1007/s00018-022-04246-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989121/
https://www.ncbi.nlm.nih.gov/pubmed/35391601
http://dx.doi.org/10.1007/s00018-022-04246-w

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