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The Role of Impaired Mitochondrial Dynamics in MFN2-Mediated Pathology
The Mitofusin 2 protein (MFN2), encoded by the MFN2 gene, was first described for its role in mediating mitochondrial fusion. However, MFN2 is now recognized to play additional roles in mitochondrial autophagy (mitophagy), mitochondrial motility, lipid transfer, and as a tether to other organelles i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989266/ https://www.ncbi.nlm.nih.gov/pubmed/35399520 http://dx.doi.org/10.3389/fcell.2022.858286 |