2,3,4′,5-Tetrahydroxystilbene-2-O-β-D-glucoside ameliorates gentamicin-induced ototoxicity by modulating autophagy via Sesn2/AMPK/mTOR signaling

Gentamicin is an important aminoglycoside antibiotic used in the treatment of gram-negative bacterial infections, but nephrotoxicity and ototoxicity reduce its utility. The autophagy pathway is involved in damage of auditory hair cells. With the aim of developing new strategies for attenuating genta...

Descripción completa

Detalles Bibliográficos
Autores principales: Wen, Yu-Hsuan, Lin, Hui-Yi, Lin, Jia-Ni, Tseng, Guo-Fang, Hwang, Chung-Feng, Lin, Chung-Ching, Hsu, Chuan-Jen, Wu, Hung-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989425/
https://www.ncbi.nlm.nih.gov/pubmed/35348190
http://dx.doi.org/10.3892/ijmm.2022.5127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989425/
https://www.ncbi.nlm.nih.gov/pubmed/35348190
http://dx.doi.org/10.3892/ijmm.2022.5127

Ejemplares similares