Dysregulated RNA polyadenylation contributes to metabolic impairment in non-alcoholic fatty liver disease

Pre-mRNA processing is an essential mechanism for the generation of mature mRNA and the regulation of gene expression in eukaryotic cells. While defects in pre-mRNA processing have been implicated in a number of diseases their involvement in metabolic pathologies is still unclear. Here, we show that...

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Detalles Bibliográficos
Autores principales: Jobbins, Andrew M, Haberman, Nejc, Artigas, Natalia, Amourda, Christopher, Paterson, Helen A B, Yu, Sijia, Blackford, Samuel J I, Montoya, Alex, Dore, Marian, Wang, Yi-Fang, Sardini, Alessandro, Cebola, Inês, Zuber, Johannes, Rashid, Sheikh Tamir, Lenhard, Boris, Vernia, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989518/
https://www.ncbi.nlm.nih.gov/pubmed/35293570
http://dx.doi.org/10.1093/nar/gkac165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989518/
https://www.ncbi.nlm.nih.gov/pubmed/35293570
http://dx.doi.org/10.1093/nar/gkac165

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