A mobile restriction–modification system provides phage defence and resolves an epigenetic conflict with an antagonistic endonuclease

Epigenetic DNA methylation plays an important role in bacteria by influencing gene expression and allowing discrimination between self-DNA and intruders such as phages and plasmids. Restriction–modification (RM) systems use a methyltransferase (MTase) to modify a specific sequence motif, thus protec...

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Detalles Bibliográficos
Autores principales: Birkholz, Nils, Jackson, Simon A, Fagerlund, Robert D, Fineran, Peter C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989522/
https://www.ncbi.nlm.nih.gov/pubmed/35286398
http://dx.doi.org/10.1093/nar/gkac147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989522/
https://www.ncbi.nlm.nih.gov/pubmed/35286398
http://dx.doi.org/10.1093/nar/gkac147

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