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A mobile restriction–modification system provides phage defence and resolves an epigenetic conflict with an antagonistic endonuclease
Epigenetic DNA methylation plays an important role in bacteria by influencing gene expression and allowing discrimination between self-DNA and intruders such as phages and plasmids. Restriction–modification (RM) systems use a methyltransferase (MTase) to modify a specific sequence motif, thus protec...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989522/ https://www.ncbi.nlm.nih.gov/pubmed/35286398 http://dx.doi.org/10.1093/nar/gkac147 |