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CFIm-mediated alternative polyadenylation remodels cellular signaling and miRNA biogenesis

The mammalian cleavage factor I (CFIm) has been implicated in alternative polyadenylation (APA) in a broad range of contexts, from cancers to learning deficits and parasite infections. To determine how the CFIm expression levels are translated into these diverse phenotypes, we carried out a multi-om...

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Detalles Bibliográficos
Autores principales: Ghosh, Souvik, Ataman, Meric, Bak, Maciej, Börsch, Anastasiya, Schmidt, Alexander, Buczak, Katarzyna, Martin, Georges, Dimitriades, Beatrice, Herrmann, Christina J, Kanitz, Alexander, Zavolan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989530/
https://www.ncbi.nlm.nih.gov/pubmed/35234914
http://dx.doi.org/10.1093/nar/gkac114