RNA polymerase pausing, stalling and bypass during transcription of damaged DNA: from molecular basis to functional consequences

Cellular DNA is continuously transcribed into RNA by multisubunit RNA polymerases (RNAPs). The continuity of transcription can be disrupted by DNA lesions that arise from the activities of cellular enzymes, reactions with endogenous and exogenous chemicals or irradiation. Here, we review available d...

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Detalles Bibliográficos
Autores principales: Agapov, Aleksei, Olina, Anna, Kulbachinskiy, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Critical Reviews and Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989532/
https://www.ncbi.nlm.nih.gov/pubmed/35323981
http://dx.doi.org/10.1093/nar/gkac174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989532/
https://www.ncbi.nlm.nih.gov/pubmed/35323981
http://dx.doi.org/10.1093/nar/gkac174

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