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RNA polymerase pausing, stalling and bypass during transcription of damaged DNA: from molecular basis to functional consequences
Cellular DNA is continuously transcribed into RNA by multisubunit RNA polymerases (RNAPs). The continuity of transcription can be disrupted by DNA lesions that arise from the activities of cellular enzymes, reactions with endogenous and exogenous chemicals or irradiation. Here, we review available d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989532/ https://www.ncbi.nlm.nih.gov/pubmed/35323981 http://dx.doi.org/10.1093/nar/gkac174 |