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Selective and stable base pairing by alkynylated nucleosides featuring a spatially-separated recognition interface

Unnatural base pairs (UBPs) which exhibit a selectivity against pairing with canonical nucleobases provide a powerful tool for the development of nucleic acid-based technologies. As an alternative strategy to the conventional UBP designs, which involve utility of different recognition modes at the W...

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Detalles Bibliográficos
Autores principales: Okamura, Hidenori, Trinh, Giang Hoang, Dong, Zhuoxin, Masaki, Yoshiaki, Seio, Kohji, Nagatsugi, Fumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989583/
https://www.ncbi.nlm.nih.gov/pubmed/35234916
http://dx.doi.org/10.1093/nar/gkac140