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Selective and stable base pairing by alkynylated nucleosides featuring a spatially-separated recognition interface
Unnatural base pairs (UBPs) which exhibit a selectivity against pairing with canonical nucleobases provide a powerful tool for the development of nucleic acid-based technologies. As an alternative strategy to the conventional UBP designs, which involve utility of different recognition modes at the W...
Autores principales: | Okamura, Hidenori, Trinh, Giang Hoang, Dong, Zhuoxin, Masaki, Yoshiaki, Seio, Kohji, Nagatsugi, Fumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989583/ https://www.ncbi.nlm.nih.gov/pubmed/35234916 http://dx.doi.org/10.1093/nar/gkac140 |
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