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Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine

We examined antibody and memory B cell responses longitudinally for ∼9–10 months after primary 2-dose SARS-CoV-2 mRNA vaccination and 3 months after a 3rd dose. Antibody decay stabilized between 6 and 9 months, and antibody quality continued to improve for at least 9 months after 2-dose vaccination....

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Detalles Bibliográficos
Autores principales: Goel, Rishi R., Painter, Mark M., Lundgreen, Kendall A., Apostolidis, Sokratis A., Baxter, Amy E., Giles, Josephine R., Mathew, Divij, Pattekar, Ajinkya, Reynaldi, Arnold, Khoury, David S., Gouma, Sigrid, Hicks, Philip, Dysinger, Sarah, Hicks, Amanda, Sharma, Harsh, Herring, Sarah, Korte, Scott, KC, Wumesh, Oldridge, Derek A., Erickson, Rachel I., Weirick, Madison E., McAllister, Christopher M., Awofolaju, Moses, Tanenbaum, Nicole, Dougherty, Jeanette, Long, Sherea, D’Andrea, Kurt, Hamilton, Jacob T., McLaughlin, Maura, Williams, Justine C., Adamski, Sharon, Kuthuru, Oliva, Drapeau, Elizabeth M., Davenport, Miles P., Hensley, Scott E., Bates, Paul, Greenplate, Allison R., Wherry, E. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989683/
https://www.ncbi.nlm.nih.gov/pubmed/35523182
http://dx.doi.org/10.1016/j.cell.2022.04.009