Cargando…

IRF4 suppresses osteogenic differentiation of BM-MSCs by transcriptionally activating miR-636/DOCK9 axis

OBJECTIVES: Osteoblasts are derived from Bone Marrow-derived Mesenchymal Stem Cells (BM-MSCs), which play an indispensable role in bone formation. In this study, the authors aim to investigate the role of IRF4 in the osteogenic differentiation of BM-MSCs and its potential molecular mechanism. METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xuepu, Zhang, Yue, Yang, Limin, Wu, Yuexin, Ma, Xiaohu, Tong, Gang, Ban, Zhaoliang, Zhao, Haosen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989710/
https://www.ncbi.nlm.nih.gov/pubmed/35397366
http://dx.doi.org/10.1016/j.clinsp.2022.100019