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The Clinical Value of Decitabine Monotherapy in Patients with Acute Myeloid Leukemia
Decitabine (5-aza-2′-deoxycytidine) is a hypomethylating agent used in the treatment of acute myeloid leukemia (AML). Decitabine inhibits DNA methyltransferases, causing DNA hypomethylation, and leading amongst others to re-expression of silenced tumor suppressor genes. Decitabine is indicated for t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Healthcare
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989816/ https://www.ncbi.nlm.nih.gov/pubmed/34786648 http://dx.doi.org/10.1007/s12325-021-01948-8 |