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Metabolic Reprogramming of Alloreactive T Cells Through TCR/MYC/mTORC1/E2F6 Signaling in aGvHD Patients

Acute graft-versus-host disease (aGvHD) is the most common complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and significantly linked with morbidity and mortality. Although much work has been engaged to investigate aGvHD pathogenesis, the understanding of alloreactive...

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Detalles Bibliográficos
Autores principales: Pan, Zengkai, Huang, Aijie, He, Yang, Zhang, Zilu, Jiang, Chuanhe, Wang, Luxiang, Qing, Kai, Zhang, Sujiang, Wang, Jianmin, Hu, Xiaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989838/
https://www.ncbi.nlm.nih.gov/pubmed/35401560
http://dx.doi.org/10.3389/fimmu.2022.850177