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Clinical and biological impact of SAMHD1 expression in mantle cell lymphoma

SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase (dNTPase) that restricts viral replication in infected cells and limits the sensitivity to cytarabine by hydrolysing its active metabolite, as recently shown in acute myeloid leukemia. Cytarabine is an essential component in the Nordic man...

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Detalles Bibliográficos
Autores principales: Merrien, Magali, Wasik, Agata M., Ljung, Elin, Morsy, Mohammad H. A., de Matos Rodrigues, Joana, Carlsten, Mattias, Rassidakis, Georgios Z., Christensson, Birger, Kolstad, Arne, Jerkeman, Mats, Ek, Sara, Herold, Nikolas, Wahlin, Björn E., Sander, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989861/
https://www.ncbi.nlm.nih.gov/pubmed/34738194
http://dx.doi.org/10.1007/s00428-021-03228-w