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Coordination between cell proliferation and apoptosis after DNA damage in Drosophila

Exposure to genotoxic stress promotes cell cycle arrest and DNA repair or apoptosis. These “life” or “death” cell fate decisions often rely on the activity of the tumor suppressor gene p53. Therefore, the precise regulation of p53 is essential to maintain tissue homeostasis and to prevent cancer dev...

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Detalles Bibliográficos
Autores principales: Ruiz-Losada, Mireya, González, Raul, Peropadre, Ana, Gil-Gálvez, Alejandro, Tena, Juan J., Baonza, Antonio, Estella, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989919/
https://www.ncbi.nlm.nih.gov/pubmed/34824391
http://dx.doi.org/10.1038/s41418-021-00898-6