Biotransformation of artemisinin to a novel derivative via ring rearrangement by Aspergillus niger

ABSTRACT: Artemisinin is a component part of current frontline medicines for the treatment of malaria. The aim of this study is to make analogues of artemisinin using microbial transformation and evaluate their in vitro antimalarial activity. A panel of microorganisms were screened for biotransforma...

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Detalles Bibliográficos
Autores principales: Luo, Jiaer, Mobley, Rebecca, Woodfine, Sian, Drijfhout, Falko, Horrocks, Paul, Ren, Xiao-Dong, Li, Wen-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Biotechnological Products and Process Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989930/
https://www.ncbi.nlm.nih.gov/pubmed/35355096
http://dx.doi.org/10.1007/s00253-022-11888-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989930/
https://www.ncbi.nlm.nih.gov/pubmed/35355096
http://dx.doi.org/10.1007/s00253-022-11888-0

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