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Biotransformation of artemisinin to a novel derivative via ring rearrangement by Aspergillus niger
ABSTRACT: Artemisinin is a component part of current frontline medicines for the treatment of malaria. The aim of this study is to make analogues of artemisinin using microbial transformation and evaluate their in vitro antimalarial activity. A panel of microorganisms were screened for biotransforma...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989930/ https://www.ncbi.nlm.nih.gov/pubmed/35355096 http://dx.doi.org/10.1007/s00253-022-11888-0 |